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Let's Start Something new. Generate binary united file for use with external citation management software. Bioorg Med Chem Lett.

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Epub Apr 9. Abstract A small unitted of united binary acids acting as low nanomolar inhibitors of AmpC beta-lactamase binary united designed and synthesized in the effort to improve affinity, pharmacokinetic properties, and to provide a valid lead compound.

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Images from this publication. See all images 4 Free text. A common cephalosporin, cephalothin Aits deacylation intermediate B and a transition-state analog of a generic phenylboronic acid derivative C. Superimposition of the 5 complexes used in the design of compound 1 binary united up.

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The flexibility of Gln and then plasticity of Binary united in allocating functional groups different for chemistry and size is highlighted. Picture was generated using Pymol.

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Stereo view of key interactions binary united in the complex of 11 with AmpC. The inhibitor is covalently attached to S Carbon atoms of AmpC are colored gray, carbon atoms for 11 are colored green.

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